Officials at the Frederick Fairgrounds said a competitor from New Jersey fell off his bike after a quick turn on the track.
They say he was going close to 50 mph and lost control while accidentally riding along the limestone cushion surrounding the race track.
Officials say they believe he sustained a possible concussion due to the fall.
"He was knocked out actually. They have him all the consideration they would anybody, they loaded him up and we actually flew him out. We don't take any changes because this actually is risky business," said Richard Riley, Barbara Fritchie Classic organizer.
EMS came out to assist the injured man's condition before he was airlifted to a nearby hospital.
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