Jefferson County Fire and Rescue say crews responded to the call around 3 p.m. along 2257 Chestnut Hill Road.
WHAG spoke with fire officials who say several neighbors called to say they saw heavy smoke. Blue Ridge Volunteer Fire Company was one of the first crews to arrive on scene. Upon arrival, the home was fully engulfed in flames. Around 30 to 40 firefighters total responded.
It took crews around 15 minutes to extinguish the fire. Firefighters are still on scene spraying down the remains of the house with water and cleaning up.
No one was home when the fire started and no injuries have been reported. Officials tell WHAG the homeowner is on their way home at this time. Red Cross has also been notified.
Fire officials say the road is still shut down at this time. They expect it to be blocked for the next hour or two.
Students from Blue Ridge Elementary in Harpers Ferry who take the bus home were being held at the school, due to the road closure.
The cause and origin of the fire is under investigation by the Fire Marshal's Office.
Copyright 2016 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.