Police released the identity of the woman killed in the crash as Ashely Brechbiel, 26, of Chambersburg.
Pennsylvania State Police say Brechbiel was traveling north on I-81, crossed over the grass median into the southbound side and struck a vehicle traveling southbound head-on.
The second car overturned, but the driver did not sustain any serious injuries.
Police say I-81 southbound between exits 20 and 24 in Franklin County was shutdown for five hours.
State Police are continuing to investigate. Stay with us for updates on this developing story.
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