The accident happened on Mapleville Road near Benevola Church Road in Boonsboro.
Police say a 17-year-old driver with four other juveniles in the car was going north on Mapleville Road when they skidded off the road and went into oncoming traffic. The driver hit another car that was traveling southbound on Mapleville Road.
At least five people, including two children were taken to Meritus Medical Center and a third person was flown to Baltimore in serious condition.
Copyright 2017 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.