Pennsylvania State Police say a horse and buggy pulled out in front of an SUV traveling westbound on the roadway, causing a collision.
All three people in the horse and buggy sustained serious injuries and were airlifted to Hershey Medical Center, according to police.
The driver of the SUV and one other person in the vehicle were unharmed.
The accident remains under investigation.
Copyright 2016 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.