FREDERICK COUNTY, MD - A 21-year-old was flown to Shock Trauma, after an accident on eastbound US 340 Sunday night.
The crash happened near the St. Marks Road. exit at 9:47 p.m. The accident closed the highway for about three hours.
State police say a 27-year-old driver, Cruz Vasquez of Washington, D.C. ran into a Jaguar.
The impact caused the Subaru Legacy to run off the road, hitting several trees.
60-year-old Som Plyraharn was taken to Frederick Memorial hospital with non-life-threatening injuries.
Christina Mills of Washington, D.C. was flown to the Shock Trauma Center in Baltimore with severe injuries.
The driver of the Subaru was not injured.
Copyright 2015 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.